Machete is a former Mexican Federale who plays by his own rules, and doesn't answer to anybody. In the wake of a harrowing encounter with feared drug lord Torrez, Machete finds himself in Texas, where the shadowy Booth offers him the opportunity to make some quick cash by assassinating the unscrupulous Senator McLaughlin. When the job goes awry and Machete realizes that he has been set up, he turns to fierce taco queen Luz, heavily armed holy man Padre and trigger-happy socialite April to show Booth that he just messed with the wrong Mexican. But before they can get to Booth, Machete's gang will have to contend with blade-wielding ICE agent Sartana, who has never met an adversary she couldn't flay.