An American film actress and former child model who subsequently appeared in magazine, newspaper and television advertising. She made her motion picture debut in the 1984 crime film Once Upon a Time in America, then, while continuing her career as a model, starred as a teenager in films such as Labyrinth and Career Opportunities. She gained critical acclaim following her work in the 1998 science fiction film Dark City and for her portrayal of Marion Silver in Darren Aronofsky's 2000 drama, Requiem for a Dream. In 2002, she won an Academy Award for Best Supporting Actress along with many other awards for her role as Alicia Nash in Ron Howard's 2001 biopic A Beautiful Mind. Other film credits include the 2003 Marvel superhero film Hulk, the 2005 thriller Dark Water, the drama Blood Diamond, the remake of The Day the Earth Stood Still and the romantic comedy He's Just Not That Into You.