| name | character |
|
Drew Barrymore
|
Karen Pomeroy
|
|
Daveigh Chase
|
Samantha Darko
|
|
Patience Cleveland
|
Roberty Sparrow / Grandma Death
|
|
James Duval
|
Frank
|
|
Beth Grant
|
Kitty Farmer
|
|
Alex Greenwald
|
Seth Devlin
|
|
Jake Gyllenhaal
|
Donnie Darko
|
|
Maggie Gyllenhaal
|
Elizabeth Darko
|
|
Mark Hoffman
|
Police Officer
|
|
David St. James
|
Bob Garland
|
|
Scotty Leavenworth
|
David
|
|
Gary Lundy
|
Sean Smith
|
|
Phyllis Lyons
|
Anne Fisher
|
|
Jazzie Mahannah
|
Joanie James
|
|
Jena Malone
|
Gretchen Ross
|
|
Kristina Malota
|
Susie Bates
|
|
Marina Malota
|
Emily Bates
|
|
Mary McDonnell
|
Mrs. Rose Darko
|
|
David Moreland
|
Principal Cole
|
|
Holmes Osborne
|
Eddie Darko
|
|
Jolene Purdy
|
Cherita Chen
|
|
Katharine Ross
|
Dr. Lilian Thurman
|
|
Patrick Swayze
|
Jim Cunningham
|
|
Arthur Taxier
|
Dr. Fisher
|
|
Noah Wyle
|
Prof. Kenneth Monnitoff
|